Novel therapeutics, enhancements to existing treatments, and new uses for existing compounds are all of interest to LSGPA. In particular, we seek potential investments in translational stage therapeutics (late preclinical to early clinical) from academic labs and young discovery companies. Innovative CROs and novel approaches to clinical trials management will also be considered.
Neal G. Simon, Ph.D.
CEO and Chairman
Location: Bethlehem, PA
|Azevan Pharmaceuticals, Inc., is a clinical stage, small molecule drug development company developing novel therapeutics to treat disorders of stress, mood, and behavior. The company’s first clinical compounds selectively block the effects of arginine vasopressin, a peptide neurohormone involved in the pathophysiology of major depression, intermittent explosive disorder, impulse control/anger disorders, and post-traumatic stress disorder (PTSD). Vasopressin receptor antagonists represent a novel mechanism of action for addressing these indications.|
William G. Hearl, Ph.D.
CEO and Chairman
Location: Rockville, MD
|Immunomic Therapeutics, Inc., (ITI) is a clinical stage biotechnology company with a novel technology called LAMP-vax for application to vaccines and vaccine immunotherapies. LAMP-vax promises to increase the effectiveness of the immune response to DNA vaccines while simplifying overall vaccine design and delivery. The technology is ideally suited for application to allergy immunotherapy.|
Location: State College, PA
|Indigo Biosciences offers to academic labs, contract research organizations, and pharmaceutical and biotechnology companies kits and services focused on nuclear receptors, an important target in new drug development, as well as the broader fields of in vitro toxicology and gene expression. Indigo’s off-the-shelf kits, in particular, are a cost-effective alternative to assays developed in-house and represent a significant improvement over the few commercially available alternatives. Each kit is self-contained, with all materials and reagents needed to test the customer’s compound. Proprietary cryo-preservation technology and low temperature packaging allow on-demand delivery to locations around the world in 24 to 36 hours.|